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Description
The predominant role of glutathione is its role in our immune system
AMP-activated protein kinase (AMPK) directly interacts with the core catalytic domain of SIRT1 and mediates phosphorylation of threonine 344 of SIRT1, which directly inhibits its deacetylation activity (81)
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Mechanism of Action Acetyl Group Protection : The attached acetyl group acts as a molecular shield, preventing digestive enzymes from breaking down glutathione prematurely in the stomach and intestines, which allows the intact molecule to reach target tissues like the liver, lungs, and brain
