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Description
Once formed, Fe-S clusters are transferred to specific recipient proteins, providing to these ones a versatile capacity to accept or donate electrons depending on redox potential, oxidation state and conformational changes

Diabetes Care 2020;43:2493-9

Redox-regulated iron metabolism and ferroptosis in ovarian cancer: molecular insights and therapeutic opportunities

These data suggest that HNE targets NLRP3, but not caspase-11
