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Description
The second stage is Trem2-dependent and is marked by increased expression of genes involves in lipid metabolism and phagocytic pathway genes (e.g., Lpl, Cst , and Cd9 ), causing excessive inflammatory responses and neurodegeneration (Keren-Shaul et al., 2017
JC: Writing original draft
doi: 10.3390/jcm14113930 65 DerkachKVBakhtyukovAARomanovaIVZorinaIIBayunovaLVBondarevaVMet al
Extended use appears well-tolerated based on available research
