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The TAS secondary endpoint did not show significant changes

Join us as we unpack the pharmacology, the clinical consequences, and why etomidate is now a substance toxicologists are watching closely

The resulting metabolite is exported via the portal vein through interacting with multidrug resistance proteins until it enters the bloodstream and reaches tissues, where it is taken up by the RFC system or by folate receptors

350 For example, aged HSCs exhibit a diminished capacity to adhere to stromal cells, which may perturb the interactions between stem cells and the hematopoietic niche, ultimately leading to alterations in the functionality of aging HSCs