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In brain and other nerve tissues, this acetyl group export by acetyl-L-carnitine out of the mitochondria into the cytosol is important in maintaining normal levels of acetyl groups for the production of acetylcholine and other acetylated neurotransmitters that are so crucial for normal brain and

Neuronal and microglial mitochondrial dysfunction in FM impairs electron transport chain (ETC) activity, leading to electron leakage and superoxide (O ) formation, which contribute to ATP deficits

These activities of ALCAR were observed not only in androgen-dependent (LNCaP cells) and androgen-independent metastatic PCa cells (PC-3 and DU145), but also in BPH cell lines, which represent a pre-neoplastic stage