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10.1016/j.neuroscience.2011.02.031 90 ShangY.ZhangZ.TianJ.LiX

The exclusion criteria were (1) non-English language articles, (2) studies not directly relevant to the proposed triad

Lipid peroxides damage cell membranes, disrupting the intestinal epithelial barrier and increasing permeability, allowing harmful substances and bacteria to enter underlying tissue and triggering an immune response (38)

HDAC6 is known for removing acetyl groups from non-histone proteins such as -tubulin, cortactin and heat shock protein 90 (HSP90), which play vital roles in preserving cell structure, movement and response to stress (8-10)