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The activation of AMPK depends on several factors, primarily energy status: as cellular ATP levels decrease, AMP (adenosine monophosphate) and ADP (adenosine diphosphate) levels increase

Kazmi et al., 2024)

cells as a way to attenuate brain damage (Wang et al., 2017
72,189 This is supported by recent work suggesting that ROS are required for Phosphatase and tensin homolog-induced kinase 1/Parkin-dependent mitophagy