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Description
The labial cortical bone of mandibular incisors is significantly thinner than the posterior mandible, allowing the local anaesthetic to diffuse efficiently toward the terminal branches of the inferior alveolar nerve
The only reliable method to ensure sterility is respecting validated use timelines: 28 days post-puncture when refrigerated, shorter if temperature excursions occurred
The addition of bacteriostatic preservatives such as benzyl alcohol became common practice during the twentieth century to allow multi-use solutions with reduced microbial contamination risk
Magis, A
