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Description
Postmortem analysis of AD patient brains revealed an accumulation of metal ions such as iron (Fe) and zinc (Zn) due to dysregulation (Lovell et al., 1998)

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The D197A mutation was then performed, with the wild-type vector as a template, by PCR using the primers 5-CCATCTCCGCCGTGGCCGATC3 and 5-GATCGGCCACGGCGGAGATGG-3 containing the mutated GCC codon, together with the 5 and 3 primers used for the cloning of MTAN

& Dragoe, N
