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Recently, increased IGF-I expression was reported in obese children with non-alcoholic fatty liver disease (NAFLD) and it was combined with upregulation of IGF1R (96), not expressed in the normal liver but involved in liver repair, such as after liver resection in a mouse model (97)

Dispose of the syringe and needle properly after use

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What they did: Isolated human chondrocytes (from osteoarthritis patients and healthy donors) were exposed to AOD-9604 at doses 1 to 1000 nM