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discovered that high ROS levels increase AP-1 (activator protein-1) and NF-B (nuclear factor B) levels, subsequently increasing the expression of matrix metalloproteinases (MMPs)

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Kim JE, Lee MH, Nam DH

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Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical Illness1

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