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The synthesis and metabolism of thyroid hormones depend on selenium

A case for alpha-lipoic acid as an alternative treatment for diabetic polyneuropathy

Both can cause fatigue and weakness

these factors make GLP-1 RAs an alternative initial treatment option, with or without metformin based on glycemic needs, in T2DM patients with indicators of high-risk or established heart failure (HF) or CKD who cannot tolerate an SGLT2 inhibitor
