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7) Liver Dysfunction In a study on over 1,600 adults, high TMAO levels were associated with more severe liver damage and non-alcoholic fatty liver disease [33]
PGC-1 upregulates mitochondrial antioxidant enzymes such as SOD2 and catalase, thereby reducing ROS-mediated damage in cells [123,124,125]
10.1038/ki.2012.345 110 VaziriN
Therefore, the biotransformation of D-carnitine or crotonobetaine into L-carnitine by resting cells of E
