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Description
When a cell over-expresses NNMT, it does two costly things at once: it burns through methyl-donor capacity, and it diverts nicotinamide away from NAD+ regeneration into an inert metabolite (1-methylnicotinamide) that gets excreted
M., Kellokoski, E., Hrkk, S., Kauma, H., Kesniemi, Y
10.1016/j.bpj.2013.07.036 107
Testing and Diagnosis Testing for MTHFR gene mutations typically involves a blood test or a cheek swab
