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No fluid retention or edema Growth hormone commonly causes water retention, leading to bloating, swelling in extremities, and a puffy appearance

Appetite and food reward 3-arm Phase 1 tirzepatide vs liraglutide 3.0 mg vs placebo: measured lunch intake fell 524.6 kcal vs placebo by week 3 (about 72% by week 6), with craving and hedonic-hunger reductions exceeding liraglutide

The conspiracy theory is that useful peptides are ignored by pharma companies because peptide drugs cannot be patented and become real medicines

Wernicke encephalopathy in subjects undergoing restrictive weight loss surgery: A systematic review of literature data
