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12 Conversely, non-RBD-PD may reflect a brain-first subtype, in which pathological -synuclein originates within the central nervous system and then spreads peripherally

Han J, Kaufman RJ

Bentham Science Publishers

In the PD model, DR-AB, an antibody that targets the DR region of the NKA- subunit, disrupts the cytoplasmic interaction between NKA-1 and Parkin, promotes Parkin translocation to mitochondria, and enhances mitochondrial autophagy
