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Parkin ubiquitinates various mitochondrial proteins [253, 277]

Dimethyl fumarate protects retinal pigment epithelium from blue light-induced oxidative damage via the nrf2 pathway

In B16F-10 melanoma-induced metastasis-bearing C57BL/6 mice, sulforaphane has been shown to enhance natural killer cell activity while also enhancing antibody-dependent cellular cytotoxicity in metastatic tumour-bearing animals [28]

Conclusions Nutraceuticals represent promising strategies for preventing, delaying, and addressing premature aging of the skin, especially as women advance in years (particularly after 30 years of age, when estrogen levels begin to decline and remarkably after menopause when estrogen production ceases from the ovaries)