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Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma

67 Non-proliferative astrogliosis typically occurs in neural tissue that is responding to a pathology but is not overtly damaged and retains its basic tissue architecture, for example (i) during diffuse neuroinflammation caused by peripheral exposure to microbial antigens such as lipopolysaccharide (LPS), 68,69 (ii) in tissue regions that are at a distance from focal lesions (diaschisis) caused by stroke, trauma or autoimmune attack, 8,70 or (iii) in tissue undergoing neurodegenerative changes
Vitamin E supplementation in diabetics has been shown to increase glutathione by up to 9% [57]

Have you considered a vitamin B12 shot