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2007 Mar;69(3):515-9

Co-administration of valproate (250 mg BID for 14 days) with phenobarbital to normal subjects (n=6) resulted in a 50% increase in half-life and a 30% decrease in plasma clearance of phenobarbital (60 mg single-dose)

This means your car feels just as punchy on the last lap of a five-minute main as it did on the first

(March 2001)
