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[PubMed] [Google Scholar] Yoshida K, Hirokawa J, Tagami S, Kawakami Y, Urata Y, Kondo T

Expectedly, depletion of cystine or inhibition of the Xc- antiporter using synthetic small molecule inhibitors including erastin, sulfasalazine, sorafenib and even excess of glutamate triggered cystine depletion, decreased GSH level and reduced GPX4 activity, culminating in ferroptosis induction

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