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You might be told to "watch and wait," which can be frustrating when youre feeling rundown

Strengthen Immune Function: Support the immune system which relies on adequate levels of B12 to function optimally

As there was no other cause for the hyperpigmentation except for a low serum vitamin B12 level, she was started on intramuscular injections of 1000 g of vitamin B12 followed by a vitamin B complex (vitamins B1, B6, and B12) tablet daily

12 , 13 Moderate physical activity and healthy diets promote a balanced microbiome (eg, a high Bacteroidetes to Firmicutes ratio) along with the production of neurotransmitters (eg, serotonin, dopamine), secondary bile acids, and short-chain fatty acids, including acetate, propionate, and butyrate (Figure 1)