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The mitochondrial pathway can be triggered by hypoxia, ROS, and DNA damage, mainly leading to apoptosis by disrupting the balance of Bcl-2 family proteins

have global membrane effects via action on lipid-rafts (Pavel et al., 2020) and alter CNS blood flow (Slupe and Kirsch, 2018)

It works by willingly donating an electron to unstable, destructive free radicals, thereby neutralizing them before they can tear through delicate cellular membranes, proteins, and mitochondrial DNA in a destructive process known as lipid peroxidation