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It appears that once daily and twice daily doses of ALCAR can achieve similar plasma levels
These findings may explain the beneficial effects of selenium supplementation in autoimmune thyroid diseases (181, 194), such as reduced levels of anti-thyroid antibodies, improved thyroid structure and metabolism, and ameliorated clinical symptoms (181, 195)

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Additional pharmacokinetic parameters (C max , T max , t 1/2 ) were calculated from plasma TMAO and L-carnitine concentrations using R package pracma (47)
