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First, while Jnk2 was globally deleted in all cell types, Jnk1 was specifically ablated in hepatocytes but present in non-parenchymal cells, implying an opposing role of Jnk1 in different subsets of liver cells as well as in infiltrated inflammatory cells

One goal is to provide an impetus to additionally investigate changes in DNA methylation as a possible consequence of an impaired methyl group metabolism

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Dies beruht auf der Tatsache, dass die Wirksamkeit der anderen Mittel in anderen Organen auf Grund ihrer cytoprotektiven Wirkungen (z