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Owing to its antioxidant and renal vasodilator properties, NAC has been extensively investigated for CIN prevention in patients undergoing coronary diagnostic and interventional procedures, with mixed results [9]

[11] Two magnesium ions function to stabilize the acylphosphate intermediate, facilitate binding of ATP, and activate removal of phosphate group from ATP

Through redox cycling, GSH donates electrons to quench free radicals and is then oxidized to glutathione disulfide (GSSG)