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Knockdown of SLC1A1 reduced cystine uptake by inhibiting glutamate transport, leading to decreased cysteine, GSH, and glutathione peroxidase 4 (GPX4) content, and the production of ROS and lipid peroxidation

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As per recent research reports, circulating TMAO is becoming known to be associated with an increasing variety of other chronic conditions, such as cancer, type 2 diabetes mellitus (T2DM), and renal disease as mentioned in Fig