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The detection of NAC and Di-NAC was monitored at an UV wavelength of 212 nm

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Somehow, the return to a functional balance between oxidant and antioxidant species favors the inhibition of pathways such as MAPK, JNK, and p38MAPK

Hence, some drug development focuses on peripherally restricted KOR agonists to retain analgesic efficacy with a more favorable adverse effect [61]
