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Although reprogramming has historically used viral vectors, recent advancements in microRNA technology has led to the development of alternative transcription factor delivery methods that have been reported to increase the conversion efficiency in vitro and in vivo from somatic cells into functional dopaminergic neurons and ameliorate motor symptoms in a model of PD

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Prxs 1 and 2 are targets for direct binding to artesunate, a derivative of the anti-malaria and anti-tumor drug artemisinin

Western blotting can be used for protein identification, protein quantification, and verification of gene expression 116