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20 There are numerous methods for detecting glutathione, with commonly used ones including the iodometric method, the DTNB (Ellman's reagent) method, the sodium nitroprusside method, the fluorometric method, the alloxan method, and high-performance liquid chromatography (HPLC)

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doi: 10.3389/fendo.2025.1613334 Received 17 April 2025 Accepted 15 August 2025 Published 02 October 2025 Volume 16 - 2025 Edited by Hong Liu, UC Davis Health, United States Reviewed by Andrei Adrian Tica, University of Medicine and Pharmacy of Craiova, Romania Tian Xia, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, China Updates Copyright 2025 Ou, Wang, Zhou, Chen, Lyu, Feng and Huang

In turn, in the VPA-induced rodent model of ASD, 4-week treatment with risperidone at both tested doses (1 and 3 mg/kg) increased Adar2 relative gene expression and decreased GluA2 Q:R ratio in the hippocampus and the PFC