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M.AloriniM.JaberF

During the acute phase, ferroptotic neurons release damage-associated molecular patterns (DAMPs), including mitochondrial DNA (mtDNA), which activates the cGAS-STING pathway in microglia, driving M1 pro-inflammatory polarization via NF-B/IRF3 signaling (Ma et al
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Sporn MB, Dunlop NM, Newton DL, Smith JM
