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The guidelines are for people at high risk to be screened with a routine blood test at least once a year

IL-17A induces ET-1 expression in keratinocytes via the p38 MAPK pathway (49)

That's reassuring for short-term tolerability, but it's two people, not a population

It's important to note that unexplained weight loss can be a sign of an underlying health condition and should be investigated by a GP
