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Description
Tirzepatide marks a new era in the pharmacotherapy of T2DM and/or obesity where double digit WL and maintenance together with excellent glycemic control and optimisation of multiple cardiometabolic risk factors is feasible through combination of gut hormones

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For example, a combination of TGF- inhibitors with PI3K/Akt pathway inhibitors could reduce myofibroblast activation and ECM production while also diminishing the survival and proliferation of this fibrotic effector cell

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