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longa are a blend of three curcuminoids: diferuloylmethane (94%, C 21 H 20 O 6 , curcumin I), demethoxycurcumin (6%, C 20 H 18 O 5 , curcumin II), and bis-demethoxycurcumin (0.3%, C 19 H 16 O 4 , curcumin III) ( 2 groups in the -diketone moiety of these compounds confer anti-inflammatory and antioxidant properties, among other bioactivities, making curcumin a valuable nutraceutical for chemo-preventive and therapeutic applications ( Furthermore, curcumin is soluble in organic solvents such as methanol, ethanol, acetone, and dimethyl sulfoxide (DMSO) but is insoluble in water

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