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The REW containing variants showed considerably enhanced CDC activity, with the most prominent effects measured at low and intermediate CD20 levels, while the effect of REW waned at higher CD20 levels and increased inherent CDC activity of the antibody variants (Fig
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Segura-Aguilar, J., Muoz, P., & Paris, I
Protection against hemagglutinin subtypes similar to the strain circulating around the time of a cohorts first influenza exposure as children appears to be stronger than against other subtypes, suggesting the strong influence of that first exposure on the immune response to all subsequent influenza exposures [122,123,124]