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Berinder, K., Akre, O., Granath, F

Autonomic nervous system dysfunction in adolescents with postural orthostatic tachycardia syndrome and chronic fatigue syndrome is characterised by attenuated vagal baroreflex and potentiated sympathetic vasomotion

Cardiovascular effects beyond cardiac hypertrophy are poorly characterized for IGF-1 DES specifically, though IGF-1 influences cardiovascular physiology through effects on vascular smooth muscle, endothelial function, blood pressure regulation, and cardiac contractility - chronic perturbation of these processes carries unknown risks
References 1 AllenJ
