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Laboratory studies investigate DSIPs effects on sleep architecture (delta wave sleep, REM sleep, sleep continuity), circadian rhythm regulation, stress-induced physiological changes, hypothalamic-pituitary-adrenal (HPA) axis function, and neuronal protection against various insults

This provides approximately 4mcg/kg for a 160lb individual, falling within the effective clinical range

Individuals considering extended protocols should discuss this temporal limitation with healthcare providers and maintain appropriate monitoring throughout treatment

doi:10.1016/j.recot.2024.07.004) Essibayi MA, Mortezaei A, Azzam AY, et al