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For histone H2b, Epitalon bound at site 3 near the N-terminal alpha helix, formed 12 docking solutions and binding via the sequence Val-Glu-Thr-Ser-Asn-Ser-Asn with an energy of 23.10 kcal/mol
Lancet Diabetes Endocrinol 2021;9:26475
Healthy controls had to have (1) no presence or history of chronic joint pain/swelling, (2) no presence of systemic diseases and (3) no positivity for ACPA or rheumatoid factor (RF)
Elevated levels of H 2 O 2 also are associated with the oxidation of other amino acids, leading to the formation of methionine sulfoxide and a variety of carbonyls
