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Description
Epitalon = the synthetic tetrapeptide Ala-Glu-Asp-Gly (AEDG)

In this regard, topical insulin therapy has been effectively used to treat challenging ocular diseases such as persistent epithelial defect, chemical corneal epithelial injury, and refractory corneal ulcers [15,16,17]
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It stimulates the synthesis of key ECM components, including collagen I and III, elastin, and various glycosaminoglycans (GAGs), by signaling through pathways such as the TGF-/SMAD cascade
