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A 4% topical niacinamide formulation was shown to be better tolerated than 4% hydroquinone cream, with almost comparable skin-lightening efficacy [140]

Although a large number of serotypes have been identified, the most extensively investigated is the serotype AAV2

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The disorder of acylcarnitine metabolism is related to the stage of liver disease, and with the deterioration of the disease, the disorder of acylcarnitine metabolism becomes more obvious [208]