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No as the body needs to absorb the single dose of B12 first
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Meta-analyses report a pattern of ALC deficiency in DPN patients 2 and a growing number of randomized controlled trials on ALC suggests that ALC is not only safe and effective, but also outperforms placebo in reducing diabetes-related neuropathic pain 3,4
10.1016/j.bbrc.2019.02.142 Summary Keywords diabetic wound, inflammatory response, mitochondrial dysfunction, mtDNA leakage, NLRP3 inflammasome, oxidative stress Citation Chen Y, Li H and He W (2026) Mitochondria-mediated inflammation and diabetic wound healing: mechanisms and therapeutic strategies
