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We initially found that RNA levels of XIST were downregulated in IFN-treated SGECs, and genistein effectively corrected this effect in a dose-dependent manner (Fig
A phase 1 trial in healthy volunteers showed promising tolerability and dose-dependent methionine reduction (84)
Abstract 1656: first-in-class, fluorinated folate receptor specific agents that target tumor cells via inhibition of serine hydroxymethyltransferase 2 (SHMT2) and 5-aminoimidazole-4-carboxamide formyltransferase (AICARFTase)
So I think those provided really nice images to look at for that
