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The clinical manifestations of SCD consist of chronic hemolytic anemia and recurrent acute vaso-occlusive pain episodes that contribute to clinical severity, morbidity, and early mortality [7]

[ Links ] Sarandol A, Sarandol E, Eker SS, Erdinc S, Vatansever E, Kirli S (2007) Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative-antioxidative systems

It is also possible that insulin resistance is the link between low GH levels and MASLD, as insulin directly suppresses pituitary GH secretion (29, 30)
