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Costs and causes of Oncology Drug Attrition with the example of insulin-like Growth Factor-1 receptor inhibitors

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.David C.N., Frias E.S., Szu J.I., Vieira P.A., Hubbard J.A., Lovelace J., Michael M., Worth D., McGovern K.E., Ethell I.M., et al
it's primarily for restoring essential nutrients quickly and effectively
Alterations in the expression or posttranslational modifications of specific molecules can determine the autophagy-mediated transition between the protection and killing of cells, but the exact mechanisms of action and the upstream molecules activating this transition remain unclear
