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In this five-year update of the ECHELON-2 trial, the frontline treatment of patients with PTCL using A + CHP continues to provide clinically meaningful improvements in PFS and OS compared to CHOP, with a manageable safety profile, including the continued resolution or improvement of peripheral neuropathy [226]

Vitamin C, Lung Function and Airway Hyperresponsiveness As asthmatics have both lower vitamin C levels and intake, the supplementation of this vitamin may ameliorate the course of asthma by lowering the number of asthma attacks (exacerbations), the asthma symptom score, the ICS need [280], and decreasing respiratory symptoms such as sore throat or cough in exercise- and cold-induced asthma after stimulation [37,39]

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Some companies market patches claiming to increase endogenous GHK production, though efficacy remains unproven