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2017;4(2):109115.:10.14283/jpad.2017.12
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KW-6356 is a second-generation A2A antagonist which has shown positive results with regard to motor progression in early-stage PD, as assessed by changes in the MDS-UPDRS motor score from baseline until the end of follow-up, both in combination with levodopa (NCT03703570) and as monotherapy (NCT02939391, Table 2) (Chen et al
[PubMed] [Google Scholar] 166.Huisman MT, Chhatta AA, van Tellingen O, et al