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[DOI] [PubMed] [Google Scholar] Blagaic AB, Blagaic V, Romic Z, Sikiric P

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Other pathologic features linked to effects of excessive GH may be observed, such as vertebral deformities and abnormal calcium levels, increased risk of cardiovascular disease, respiratory comorbidities, and glucose intolerance

This change in available IGF-1 may be (it is difficult to extrapolate data from altered IGF-1/GH concentrations from animal models, as each author measures IGF-1 levels using different methods) adequate for fatty acid (FA) oxidation in muscle, suppression of GH, stimulation of glucose transport into muscle [171, 172], and lastly for the suppression of renal gluconeogenesis in mice [163]