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Description
The interactions of ligand receptor lead to adsorption and autophosphorylation in the GHR cytoplasmic domain, and the JAK2/GHR complex subsequently phosphorylates STAT molecules, modifies gene transcription, and significantly results in influences on the cell proliferation

[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Juby A., Hanly M., Lukaczer D
Loss of PTEN facilitates HIF-1-mediated gene expression

& Moss, S