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Table 4 Level of GSH, GSSG, CYS, and CYSS in different tissues and erythrocytes on d5 and 14 (n = 78)

severe to critical disease)

Discussion There is an exponential increase in publications suggesting that drug-induced liver injury, especially APAP hepatotoxicity, involves ferroptosis

However it has been reported that the reduction rate of cis,cis,trans-[Pt(NH 3 ) 2 Cl 2 (RCOO)(OH)] monocarboxylato complexes is faster than that of dicarboxylato complexes and this has been attributed to the fact that hydroxido ligands are much better bridging ligands for electron transfer than carboxylate ligands 45
