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A significant model was found [ F (3, 76) = 4.9, p = 0.003], including the predictors AGE (Beta = 0.321, t = 3.0, p = 0.003, VIF = 1.010), CAARMS Perceptual Abnormalities (Beta = 0.198, t = 1.8, p = 0.081, VIF = 1.134), and CAARMS Disorganized Speech (Beta = 0.226, t = 2.0, p = 0.047, VIF = 1.133) items, that showed the same trend for both groups (Figure 2)

CD36: cluster of differentiation 36

Biology (Basel) 12:32

Clearly, these limitations need to be addressed, together with Mendelian randomization, 395,396 to draw firm conclusions on the causal relationship between the intervention and the measured clinical outcome