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In the first reaction, NADPH is consumed by AR, which can result in OxS since NADPH is required for reducing GSSG to GSH (by GR) and GSH is required for the reducing peroxides by the GPX system (see Figure 2)
Autophagy is an intracellular process that maintains cellular homeostasis through degradation and recycling of organelles
52 Further, the safety and tolerability of MSCs as a treatment for AD have been shown in a phase 1 clinical trial
